E03 Association study of cannabinoid receptor gene (CNR1) polymorphisms and age at onset in HD

BackgroundHuntington disease (HD) is caused by the expansion of a CAG repeat within exon 1 of the huntingtin (HTT) gene. Although the variation in age at onset (AO) is partly explained by the lengths of the expanded repeat, the unexplained variation in AO is heritable, emphasising the role of modifi...

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Veröffentlicht in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2012-09, Vol.83 (Suppl 1), p.A20-A20
Hauptverfasser: Kloster, E, Saft, C, Arning, L
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Sprache:eng
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