Effects of cigarette smoke extracts on apoptosis and oxidative stress in two models of ovarian cancer in vitro

Cigarette smoke contains thousands of harmful components, many of which exert toxic effects on reproductive organs, including the ovaries, and their development. In this study, we investigated the effects of cigarette smoke extract (CSE) on cell proliferation, apoptosis and oxidative stress in the S...

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Veröffentlicht in:	Toxicology in vitro 2018-10, Vol.52, p.161-169
Hauptverfasser:	Kim, Cho-Won, Go, Ryeo-Eun, Hwang, Kyung-A, Bae, Ok-Nam, Lee, Kyuhong, Choi, Kyung-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Assaying Bcl-2 protein Biotechnology Cancer Cell cycle Cell growth Cell proliferation Cigarette smoke Cigarette smoke extract ER-stress Hydrogen peroxide Inhibition Organs Ovarian cancer Ovarian cancer cells Ovaries Oxidative stress Proteins Reactive oxygen species Reproductive organs ROS Signal transduction Smoke Smoking Time dependence Toxicity Tumor cell lines TUNEL
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