Current and Investigational Agents Targeting the Phosphoinositide 3‐Kinase Pathway

Prevalent molecular alterations of the phosphoinositide 3‐kinase (PI3K) pathway are found on solid tumors and are expressed in leukocytes, making it a desirable target in both solid and hematologic malignancies. In recent years, two agents targeting this pathway have been approved by the United Stat...

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Veröffentlicht in:	Pharmacotherapy 2018-10, Vol.38 (10), p.1058-1067
Hauptverfasser:	Tang, Laura A., Dixon, Brianne N., Maples, Kathryn T., Poppiti, Kristen M., Peterson, Tim J.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase copanlisib idelalisib Leukocytes phosphoinositide 3‐kinase pathway PI3K Solid tumors Toxicity
Online-Zugang:	Volltext
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