The interaction mechanism of nifedipine and pepsin

The interaction mechanism between nifedipine (NDP) and pepsin (PEP) at 298, 310, and 318 K was studied by various spectroscopic techniques and molecular docking. The experimental results showed that NDP mainly quenched the fluorescence of PEP by dynamic quenching of non-radiative energy transfer, bu...

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Veröffentlicht in:	Monatshefte für Chemie 2018-11, Vol.149 (11), p.2123-2130
Hauptverfasser:	Ma, Lihua, Liu, Baosheng, Wang, Chundan, Zhang, Hongcai, Cheng, Xu
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Binding sites Chemistry Chemistry and Materials Science Chemistry/Food Science Computer simulation Energy transfer Fluorescence Hydrogen bonding Inorganic Chemistry Molecular docking Organic Chemistry Original Paper Pepsin Physical Chemistry Proteins Theoretical and Computational Chemistry
Online-Zugang:	Volltext
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