Rational engineering of synergically stabilized aptamer-cDNA duplex probes for strand displacement based electrochemical sensors

Electrochemical aptamer (EA) sensors employing electrode-bound aptamer-cDNA (cDNA: complementary DNA) duplex probes are simple and versatile sensing platforms for detection of many analytes. Target recognition in these sensors is a strand displacement process where target binding to aptamer displace...

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Veröffentlicht in:	Electrochimica acta 2018-08, Vol.282, p.588-594
Hauptverfasser:	Zhang, Ziping, Dong, Liping, Zhu, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamer Binding Chemical sensors Deoxyribonucleic acid Displacement DNA Duplex plating Electrochemical sensors Electrodes Optimization Peptides Sensors Stabilization Strand displacement Synergic stabilization Target detection Target recognition
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