Development of PVA Copolyme Capsules

When a solubilizing agent with a high water content is filled into a capsule, the moisture causes the capsule shell to soften and/or deform. This can be prevented by controlling the water content of the agent and the humidity of the manufacturing environment, and by using moisture-proof packaging, a...

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Veröffentlicht in:Pharmaceutical technology Europe 2004-04, Vol.16 (4), p.37
Hauptverfasser: Hoshi, Noboru, Ogura, Toshihiro, Shimamoto, Toshio, Uramatsu, Shunji
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container_issue 4
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container_title Pharmaceutical technology Europe
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creator Hoshi, Noboru
Ogura, Toshihiro
Shimamoto, Toshio
Uramatsu, Shunji
description When a solubilizing agent with a high water content is filled into a capsule, the moisture causes the capsule shell to soften and/or deform. This can be prevented by controlling the water content of the agent and the humidity of the manufacturing environment, and by using moisture-proof packaging, as done for conventional capsules. Comparison with conventional capsules. Current commercially available hard capsules are made of gelatin or HPMC.
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source EBSCOhost Business Source Complete; EZB-FREE-00999 freely available EZB journals
subjects Bioavailability
Drug dosages
Drugs
Manufacturers
Manufacturing
Moisture absorption
Permeability
Pharmaceutical industry
Pharmaceuticals
Physical properties
Polymer solubility
Polymers
Polyvinyl alcohol
title Development of PVA Copolyme Capsules
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