Transition-metal-free direct C-3 alkylation of quinoxalin-2(1 H )-ones with ethers

A convenient and efficient transition-metal-free protocol for the synthesis of 3-alkyl quinoxalin-2(1 H )-ones from the radical reaction of quinoxalin-2(1 H )-ones with ethers was developed with moderate to good yields. The methodology shows broad substrate scope, excellent functional group toleranc...

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Veröffentlicht in:	Organic Chemistry Frontiers 2018-10, Vol.5 (19), p.2820-2828
Hauptverfasser:	Yuan, Jinwei, Fu, Junhao, Yin, Jihong, Dong, Zhenhua, Xiao, Yongmei, Mao, Pu, Qu, Lingbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Atom economy Chemical synthesis Ethers Functional groups Metals Organic chemistry Substrates
Online-Zugang:	Volltext
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