Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension

Hypoxia is a common cause of persistant pulmonary hypertension in the newborn (PPHN), a condition associated with endothelial dysfunction and abnormal pulmonary vascular remodeling. The GTPase RhoA has been implicated in the pathogenesis of PPHN, but its contribution to endothelial remodeling and fu...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2006-06, Vol.34 (6), p.L1173
Hauptverfasser:	Wojciak-Stothard, Beata, Lillian Yen Fen Tsang, Paleolog, Ewa, Hall, Susan M, Haworth, Sheila G
Format:	Artikel
Sprache:	eng
Schlagworte:	Genotype & phenotype Hypertension Hypoxia Permeability Pulmonary arteries Respiratory system
Online-Zugang:	Volltext
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