Serine proteases increase oxidative stress in lung cells
Several serine proteases are directly cytotoxic. We investiated whether the cytotoxic effects of proteases are associated with increased levels of reactive oxygen species (ROS) in cells.
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Veröffentlicht in: | American journal of physiology. Lung cellular and molecular physiology 2001-09, Vol.25 (3), p.L556-L564 |
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container_title | American journal of physiology. Lung cellular and molecular physiology |
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creator | AOSHIBA, Kazutetsu YASUDA, Kimihiko YASUI, Shuji TAMAOKI, J. U. N NAGAI, Atsushi |
description | Several serine proteases are directly cytotoxic. We investiated whether the cytotoxic effects of proteases are associated with increased levels of reactive oxygen species (ROS) in cells. |
format | Article |
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U. N ; NAGAI, Atsushi</creator><creatorcontrib>AOSHIBA, Kazutetsu ; YASUDA, Kimihiko ; YASUI, Shuji ; TAMAOKI, J. U. N ; NAGAI, Atsushi</creatorcontrib><description>Several serine proteases are directly cytotoxic. We investiated whether the cytotoxic effects of proteases are associated with increased levels of reactive oxygen species (ROS) in cells.</description><identifier>ISSN: 1040-0605</identifier><identifier>EISSN: 1522-1504</identifier><identifier>CODEN: APLPE7</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Air breathing ; Biological and medical sciences ; Cells ; Cellular biology ; Fundamental and applied biological sciences. Psychology ; Lungs ; Oxidation ; Oxygen ; Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics ; Vertebrates: respiratory system</subject><ispartof>American journal of physiology. 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ispartof | American journal of physiology. Lung cellular and molecular physiology, 2001-09, Vol.25 (3), p.L556-L564 |
issn | 1040-0605 1522-1504 |
language | eng |
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source | American Physiological Society; EZB-FREE-00999 freely available EZB journals |
subjects | Air breathing Biological and medical sciences Cells Cellular biology Fundamental and applied biological sciences. Psychology Lungs Oxidation Oxygen Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics Vertebrates: respiratory system |
title | Serine proteases increase oxidative stress in lung cells |
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