Serine proteases increase oxidative stress in lung cells

Several serine proteases are directly cytotoxic. We investiated whether the cytotoxic effects of proteases are associated with increased levels of reactive oxygen species (ROS) in cells.

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Veröffentlicht in:American journal of physiology. Lung cellular and molecular physiology 2001-09, Vol.25 (3), p.L556-L564
Hauptverfasser: AOSHIBA, Kazutetsu, YASUDA, Kimihiko, YASUI, Shuji, TAMAOKI, J. U. N, NAGAI, Atsushi
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container_title American journal of physiology. Lung cellular and molecular physiology
container_volume 25
creator AOSHIBA, Kazutetsu
YASUDA, Kimihiko
YASUI, Shuji
TAMAOKI, J. U. N
NAGAI, Atsushi
description Several serine proteases are directly cytotoxic. We investiated whether the cytotoxic effects of proteases are associated with increased levels of reactive oxygen species (ROS) in cells.
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ispartof American journal of physiology. Lung cellular and molecular physiology, 2001-09, Vol.25 (3), p.L556-L564
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source American Physiological Society; EZB-FREE-00999 freely available EZB journals
subjects Air breathing
Biological and medical sciences
Cells
Cellular biology
Fundamental and applied biological sciences. Psychology
Lungs
Oxidation
Oxygen
Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics
Vertebrates: respiratory system
title Serine proteases increase oxidative stress in lung cells
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