Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca^sup 2+^ in human pulmonary arterial smooth muscle and endothelial cells

Acute pulmonary embolism occurs in more than half a million people a year in the United States. Chronic thromboembolic pulmonary hypertension (CTEPH) develops in ~4% of these patients due to unresolved thromboemboli. CTEPH is thus a relatively common, progressive, and potentially fatal disease. One...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2009-06, Vol.296 (6), p.L979
Hauptverfasser:	Firth, Amy L, Yau, Jocelyn, White, Amanda, Chiles, Peter G, Marsh, James J, Morris, Timothy A, Yuan, Jason X-J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells Lungs Proteins Pulmonary arteries Studies Thrombosis
Online-Zugang:	Volltext
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