Design, synthesis and biological evaluation of quinoxaline N-propionic and O-propionic hydrazide derivatives as antibacterial and antifungal agents

Novel series of quinaxoline derivatives incorporating N -propionic and O -propionic hydrazide moieties were synthesized. Alkylation of 3-methylquinoxalin-2(1 H )-one with ethyl 2-bromopropanoate afforded a mixture of O -alkylated and N -alkylated 3-methylquinoxaline. Hydrazide derivatives were affor...

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Veröffentlicht in:Medicinal chemistry research 2018-10, Vol.27 (10), p.2287-2296
Hauptverfasser: El Shehry, Mohamed F., Abbas, Samir Y., Farrag, Amel M., Eissa, Sally I., Fouad, Sawsan A., Ammar, Yousry A.
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Sprache:eng
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