Design, synthesis and biological evaluation of quinoxaline N-propionic and O-propionic hydrazide derivatives as antibacterial and antifungal agents
Novel series of quinaxoline derivatives incorporating N -propionic and O -propionic hydrazide moieties were synthesized. Alkylation of 3-methylquinoxalin-2(1 H )-one with ethyl 2-bromopropanoate afforded a mixture of O -alkylated and N -alkylated 3-methylquinoxaline. Hydrazide derivatives were affor...
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Veröffentlicht in: | Medicinal chemistry research 2018-10, Vol.27 (10), p.2287-2296 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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