The Three S's for Aptamer‐Mediated Control of DNA Nanostructure Dynamics: Shape, Self‐Complementarity, and Spatial Flexibility

DNA aptamers are ideal tools to enable modular control of the dynamics of DNA nanostructures. For molecular recognition, they have a particular advantage over antibodies in that they can be integrated into DNA nanostructures in a bespoke manner by base pairing or nucleotide extension without any com...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2018-09, Vol.19 (18), p.1900-1906
Hauptverfasser:	Shiu, Simon Chi‐Chin, Kinghorn, Andrew B., Sakai, Yusuke, Cheung, Yee‐Wai, Heddle, Jonathan G., Tanner, Julian A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Aptamers Aptamers, Nucleotide - chemistry Base Sequence Complementarity Deoxyribonucleic acid Diagnostic software Diagnostic systems DNA DNA - chemistry Dynamics Flexibility Models, Molecular nanomachines Nanostructure Nanostructures - chemistry Nanotechnology Nucleic Acid Conformation Nucleic acids structural optimization
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