Effects of Topically Applied Acitretin in Reconstructed Human Epidermis and the Rhino Mouse

Oral acitretin is currently indicated for the treatment of severe psoriasis in adults, but its use is limited by systemic side effects and teratogenicity. Topical administration of acitretin may lessen the risk of systemic toxicity while increasing local bioavailability in the skin. The effects of t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of investigative dermatology 2008-01, Vol.128 (1), p.125-130
Hauptverfasser:	Hsia, Edward, Johnston, Michael J., Houlden, Robert J., Chern, Wendy H., Hofland, Hans E.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acitretin - administration & dosage Administration, Topical Animals Biological and medical sciences Dermatology Disease Models, Animal Epidermis - drug effects Female Humans Interleukin-1alpha - secretion Interleukin-8 - secretion Keratin-10 - analysis Keratin-19 - analysis Keratolytic Agents - administration & dosage Male Medical sciences Mice Mice, Hairless Nicotinic Acids - administration & dosage Psoriasis - drug therapy Tretinoin - administration & dosage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!