Enhanced biosynthesis and characterization of surfactin isoforms with engineered Bacillus subtilis through promoter replacement and Vitreoscilla hemoglobin co-expression

[Display omitted] •An engineered Bacillus subtilis with high surfactin titer 10.2 g/L was constructed.•Vitreoscilla hemoglobin co-expression successfully enhanced surfactin biosynthesis.•Surfactin isoform C15 showed the best surface activity of the surfactin products. The surfactin produced by Bacil...

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Veröffentlicht in:	Process biochemistry (1991) 2018-07, Vol.70, p.36-44
Hauptverfasser:	Wang, Qi, Yu, Huimin, Wang, Miaomiao, Yang, Huan, Shen, Zhongyao
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis Bacteria Biosynthesis Dissolved oxygen Enhanced oil recovery Fermentation Hemoglobin Isoforms Oil recovery Promoter replacement Shaking Surface activity Surface tension Surfactants Surfactin Surfactin isoforms Vitreoscilla hemoglobin
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