Phenotypic Characterization of Human CD4+ Regulatory T Cells Obtained from Cutaneous Dinitrochlorobenzene-Induced Delayed Type Hypersensitivity Reactions

In this study, we describe the generation and characterization of cloned human CD4+ T lymphocyte populations that have infiltrated into cutaneous, 2,4-dinitrochlorobenzene-induced delayed type hypersensitivity reactions in healthy human subjects. It is shown that, in addition to T helper type 1 clon...

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Veröffentlicht in:	Journal of investigative dermatology 2001-08, Vol.117 (2), p.318-325
Hauptverfasser:	Lécart, Sandrine, Boulay, Vera, Raison-Peyron, Nadia, Bousquet, Jean, Yssel, Hans, Pène, Jérôme, Meunier, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases allergy Biological and medical sciences CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - immunology Cell Differentiation - immunology Cells, Cultured cytokines Dendritic Cells - cytology Dendritic Cells - immunology Dinitrochlorobenzene - administration & dosage DNA Primers Gene Expression - immunology hapten Haptens - administration & dosage human Humans Hypersensitivity, Delayed - chemically induced Hypersensitivity, Delayed - immunology Immunopathology Immunophenotyping Interferon-gamma - genetics Interferon-gamma - immunology Interleukin-1 Receptor-Like 1 Protein interleukin-10 Interleukin-10 - genetics Interleukin-4 - genetics Interleukin-4 - immunology Irritants - administration & dosage Isoantigens - genetics Isoantigens - immunology Medical sciences Membrane Proteins Monocytes - cytology Monocytes - immunology Proteins - genetics Proteins - immunology Receptors, Cell Surface Receptors, Interleukin - genetics Receptors, Interleukin - immunology Receptors, Interleukin-12 RNA, Messenger - analysis skin Skin allergic diseases. Stinging insect allergies T lymphocytes Th2 Cells - cytology Th2 Cells - immunology
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