The Relationship Between Insulin Resistance and Pulmonary Functions in Morbidly Obese Patients
Background: Insulin resistance (IR) caused by obesity-related inflammation was previously reported to be a risk factor for impaired pulmonary functions. Most studies addressed asthma or asthma-like symptoms, whereas very few addressed objective measures. We aimed to investigate the association betwe...
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| Veröffentlicht in: | Bariatric surgical practice and patient care 2018-09, Vol.13 (3), p.121-127 |
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| container_title | Bariatric surgical practice and patient care |
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| creator | Uzumcugil, Filiz Ozkaragoz, Demet Basak Ankay Yilbas, Aysun Akca, Basak Pamuk, Almıla Gulsun |
| description | Background: Insulin resistance (IR) caused by obesity-related inflammation was previously reported to be a risk factor for impaired pulmonary functions. Most studies addressed asthma or asthma-like symptoms, whereas very few addressed objective measures. We aimed to investigate the association between IR and pulmonary functions by evaluating FEV1, FVC, and FEV1/FVC in morbidly obese patients. Materials and Methods: Preanesthetic evaluation records of patients who underwent bariatric surgery were obtained. The presence of IR and metabolic syndrome (MetS) was analyzed for their correlations with the number of patients with FEV1, FVC, and FEV1/FVC measures lower than lower limit of normal (LLN). FEV1, FVC, and FEV1/FVC were analyzed as continuous variables for correlations with homeostasis model assessment of IR (HOMA-IR), body mass index (BMI), and fasting insulin. Results: There was no association between IR and FEV1, FVC, or FEV1/FVC. BMI, HOMA-IR scores, and fasting insulin levels were not correlated with FEV1/FVC. The number of patients whose FEV1, FVC, and FEV1/FVC were |
| doi_str_mv | 10.1089/bari.2017.0053 |
| format | Article |
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Most studies addressed asthma or asthma-like symptoms, whereas very few addressed objective measures. We aimed to investigate the association between IR and pulmonary functions by evaluating FEV1, FVC, and FEV1/FVC in morbidly obese patients. Materials and Methods: Preanesthetic evaluation records of patients who underwent bariatric surgery were obtained. The presence of IR and metabolic syndrome (MetS) was analyzed for their correlations with the number of patients with FEV1, FVC, and FEV1/FVC measures lower than lower limit of normal (LLN). FEV1, FVC, and FEV1/FVC were analyzed as continuous variables for correlations with homeostasis model assessment of IR (HOMA-IR), body mass index (BMI), and fasting insulin. Results: There was no association between IR and FEV1, FVC, or FEV1/FVC. BMI, HOMA-IR scores, and fasting insulin levels were not correlated with FEV1/FVC. The number of patients whose FEV1, FVC, and FEV1/FVC were <LLN was similar in nondiabetic patients with or without IR and in patients with or without MetS. Despite statistical insignificance, the number of patients with FEV1<LLN was higher in patients with IR (p = 0.106). Conclusions: We found no association between IR and FEV1, FVC, or FEV1/FVC in morbidly obese patients.</description><identifier>ISSN: 2168-023X</identifier><identifier>EISSN: 2168-0248</identifier><identifier>DOI: 10.1089/bari.2017.0053</identifier><language>eng</language><publisher>New Rochelle: Mary Ann Liebert, Inc</publisher><subject>Adults ; Anesthesiology ; Asthma ; Body mass index ; Cholesterol ; Diabetes ; Gastrointestinal surgery ; Insulin resistance ; Lungs ; Medicine ; Metabolic syndrome ; Obesity</subject><ispartof>Bariatric surgical practice and patient care, 2018-09, Vol.13 (3), p.121-127</ispartof><rights>(©) Copyright 2018, Mary Ann Liebert, Inc., publishers</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c267t-e55f3917a0a55b9b9bc158ccc60bd1858fc45646319bd4ac3c24b142ef2bf5103</citedby><cites>FETCH-LOGICAL-c267t-e55f3917a0a55b9b9bc158ccc60bd1858fc45646319bd4ac3c24b142ef2bf5103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Uzumcugil, Filiz</creatorcontrib><creatorcontrib>Ozkaragoz, Demet Basak</creatorcontrib><creatorcontrib>Ankay Yilbas, Aysun</creatorcontrib><creatorcontrib>Akca, Basak</creatorcontrib><creatorcontrib>Pamuk, Almıla Gulsun</creatorcontrib><title>The Relationship Between Insulin Resistance and Pulmonary Functions in Morbidly Obese Patients</title><title>Bariatric surgical practice and patient care</title><description>Background: Insulin resistance (IR) caused by obesity-related inflammation was previously reported to be a risk factor for impaired pulmonary functions. Most studies addressed asthma or asthma-like symptoms, whereas very few addressed objective measures. We aimed to investigate the association between IR and pulmonary functions by evaluating FEV1, FVC, and FEV1/FVC in morbidly obese patients. Materials and Methods: Preanesthetic evaluation records of patients who underwent bariatric surgery were obtained. The presence of IR and metabolic syndrome (MetS) was analyzed for their correlations with the number of patients with FEV1, FVC, and FEV1/FVC measures lower than lower limit of normal (LLN). FEV1, FVC, and FEV1/FVC were analyzed as continuous variables for correlations with homeostasis model assessment of IR (HOMA-IR), body mass index (BMI), and fasting insulin. Results: There was no association between IR and FEV1, FVC, or FEV1/FVC. BMI, HOMA-IR scores, and fasting insulin levels were not correlated with FEV1/FVC. The number of patients whose FEV1, FVC, and FEV1/FVC were <LLN was similar in nondiabetic patients with or without IR and in patients with or without MetS. Despite statistical insignificance, the number of patients with FEV1<LLN was higher in patients with IR (p = 0.106). Conclusions: We found no association between IR and FEV1, FVC, or FEV1/FVC in morbidly obese patients.</description><subject>Adults</subject><subject>Anesthesiology</subject><subject>Asthma</subject><subject>Body mass index</subject><subject>Cholesterol</subject><subject>Diabetes</subject><subject>Gastrointestinal surgery</subject><subject>Insulin resistance</subject><subject>Lungs</subject><subject>Medicine</subject><subject>Metabolic syndrome</subject><subject>Obesity</subject><issn>2168-023X</issn><issn>2168-0248</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNo9kN9LwzAQx4MoOOZefQ743JofTdo-6nA6mGzIBJ8MSXplHV06kxbZf2_qxLuHO7jvfY_7IHRLSUpJUd4b7ZuUEZqnhAh-gSaMyiIhLCsu_3v-cY1mIexJjJxInvMJ-tzuAL9Bq_umc2HXHPEj9N8ADi9dGNrGxWFoQq-dBaxdhTdDe-ic9ie8GJz93cJR9dp501TtCa8NBMCb6AeuDzfoqtZtgNlfnaL3xdN2_pKs1s_L-cMqsUzmfQJC1LykuSZaCFPGtFQU1lpJTEULUdQ2EzKTnJamyrTllmWGZgxqZmpBCZ-iu7Pv0XdfA4Re7bvBu3hSsTgmXDIhoio9q6zvQvBQq6NvDvEXRYkaMaoRoxoxqhEj_wFpOmZ7</recordid><startdate>201809</startdate><enddate>201809</enddate><creator>Uzumcugil, Filiz</creator><creator>Ozkaragoz, Demet Basak</creator><creator>Ankay Yilbas, Aysun</creator><creator>Akca, Basak</creator><creator>Pamuk, Almıla Gulsun</creator><general>Mary Ann Liebert, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K6X</scope><scope>KB0</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>201809</creationdate><title>The Relationship Between Insulin Resistance and Pulmonary Functions in Morbidly Obese Patients</title><author>Uzumcugil, Filiz ; Ozkaragoz, Demet Basak ; Ankay Yilbas, Aysun ; Akca, Basak ; Pamuk, Almıla Gulsun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-e55f3917a0a55b9b9bc158ccc60bd1858fc45646319bd4ac3c24b142ef2bf5103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adults</topic><topic>Anesthesiology</topic><topic>Asthma</topic><topic>Body mass index</topic><topic>Cholesterol</topic><topic>Diabetes</topic><topic>Gastrointestinal surgery</topic><topic>Insulin resistance</topic><topic>Lungs</topic><topic>Medicine</topic><topic>Metabolic syndrome</topic><topic>Obesity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Uzumcugil, Filiz</creatorcontrib><creatorcontrib>Ozkaragoz, Demet Basak</creatorcontrib><creatorcontrib>Ankay Yilbas, Aysun</creatorcontrib><creatorcontrib>Akca, Basak</creatorcontrib><creatorcontrib>Pamuk, Almıla Gulsun</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>British Nursing Index</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Bariatric surgical practice and patient care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Uzumcugil, Filiz</au><au>Ozkaragoz, Demet Basak</au><au>Ankay Yilbas, Aysun</au><au>Akca, Basak</au><au>Pamuk, Almıla Gulsun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Relationship Between Insulin Resistance and Pulmonary Functions in Morbidly Obese Patients</atitle><jtitle>Bariatric surgical practice and patient care</jtitle><date>2018-09</date><risdate>2018</risdate><volume>13</volume><issue>3</issue><spage>121</spage><epage>127</epage><pages>121-127</pages><issn>2168-023X</issn><eissn>2168-0248</eissn><abstract>Background: Insulin resistance (IR) caused by obesity-related inflammation was previously reported to be a risk factor for impaired pulmonary functions. Most studies addressed asthma or asthma-like symptoms, whereas very few addressed objective measures. We aimed to investigate the association between IR and pulmonary functions by evaluating FEV1, FVC, and FEV1/FVC in morbidly obese patients. Materials and Methods: Preanesthetic evaluation records of patients who underwent bariatric surgery were obtained. The presence of IR and metabolic syndrome (MetS) was analyzed for their correlations with the number of patients with FEV1, FVC, and FEV1/FVC measures lower than lower limit of normal (LLN). FEV1, FVC, and FEV1/FVC were analyzed as continuous variables for correlations with homeostasis model assessment of IR (HOMA-IR), body mass index (BMI), and fasting insulin. Results: There was no association between IR and FEV1, FVC, or FEV1/FVC. BMI, HOMA-IR scores, and fasting insulin levels were not correlated with FEV1/FVC. The number of patients whose FEV1, FVC, and FEV1/FVC were <LLN was similar in nondiabetic patients with or without IR and in patients with or without MetS. Despite statistical insignificance, the number of patients with FEV1<LLN was higher in patients with IR (p = 0.106). Conclusions: We found no association between IR and FEV1, FVC, or FEV1/FVC in morbidly obese patients.</abstract><cop>New Rochelle</cop><pub>Mary Ann Liebert, Inc</pub><doi>10.1089/bari.2017.0053</doi><tpages>7</tpages></addata></record> |
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| language | eng |
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| source | Alma/SFX Local Collection |
| subjects | Adults Anesthesiology Asthma Body mass index Cholesterol Diabetes Gastrointestinal surgery Insulin resistance Lungs Medicine Metabolic syndrome Obesity |
| title | The Relationship Between Insulin Resistance and Pulmonary Functions in Morbidly Obese Patients |
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