Crystals cause acute necrotic cell death in renal proximal tubule cells, but not in collecting tubule cells

Crystals cause acute necrotic cell death in renal proximal tubule cells, but not in collecting tubule cells. The interaction between renal tubular cells and crystals generated in the tubular fluid could play an initiating role in the pathophysiology of calcium oxalate nephrolithiasis. Crystals are e...

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Veröffentlicht in:	Kidney international 2005-10, Vol.68 (4), p.1543-1553
Hauptverfasser:	Schepers, Marieke S.J., Van Ballegooijen, Eddy S., Bangma, Chris H., Verkoelen, Carl F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Biological and medical sciences Calcium Oxalate - chemistry Calcium Oxalate - toxicity calcium oxalate crystals Cell death collecting tubule cells Crystallization Culture Media Dinoprostone - metabolism Dogs Humans Hydrogen Peroxide - metabolism inflammation Kidney Calculi - chemistry Kidney Calculi - metabolism Kidney Calculi - pathology Kidney Tubules, Collecting - drug effects Kidney Tubules, Collecting - metabolism Kidney Tubules, Collecting - pathology Kidney Tubules, Proximal - drug effects Kidney Tubules, Proximal - metabolism Kidney Tubules, Proximal - pathology LLC-PK1 Cells Medical sciences Necrosis necrotic cell death Nephrology. Urinary tract diseases renal proximal Swine Thymidine - pharmacokinetics Tritium
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