Endophytic fungi isolated from medicinal plants: future prospects of bioactive natural products from Tabebuia/Handroanthus endophytes
Medicinal plants are a rich source of natural products used to treat many diseases; therefore, they are the basis for a new drug discovery. Plants are capable of generating different bioactive secondary metabolites, but a large amount of botanical material is often necessary to obtain small amounts...
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| Veröffentlicht in: | Applied microbiology and biotechnology 2018-11, Vol.102 (21), p.9105-9119 |
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| creator | Gómez, Omar Cabezas Luiz, Jaine Honorata Hortolan |
| description | Medicinal plants are a rich source of natural products used to treat many diseases; therefore, they are the basis for a new drug discovery. Plants are capable of generating different bioactive secondary metabolites, but a large amount of botanical material is often necessary to obtain small amounts of the target substance. Nowadays, many medicinal plants are becoming rather scarce. For this reason, it is important to point out the interactions between endophytic microorganisms and the host plant, because endophytes are able to produce highly diverse compounds, including those from host plants that have important biological activities. Thence, this review aims at presenting the richness in bioactive compounds of the medicinal plants from
Tabebuia
and
Handroanthus
genera, as well as important aspects about endophyte-plant interactions, with emphasis on the production of bioactive compounds by endophytic fungi, which has been isolated from various medicinal plants for such a purpose. Furthermore, bio-prospection of natural products synthesized by endophytes isolated from the aforementioned genera used in traditional medicine could be used to treat illnesses. |
| doi_str_mv | 10.1007/s00253-018-9344-3 |
| format | Article |
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Tabebuia
and
Handroanthus
genera, as well as important aspects about endophyte-plant interactions, with emphasis on the production of bioactive compounds by endophytic fungi, which has been isolated from various medicinal plants for such a purpose. Furthermore, bio-prospection of natural products synthesized by endophytes isolated from the aforementioned genera used in traditional medicine could be used to treat illnesses.</description><identifier>ISSN: 0175-7598</identifier><identifier>EISSN: 1432-0614</identifier><identifier>DOI: 10.1007/s00253-018-9344-3</identifier><identifier>PMID: 30203146</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Bioactive compounds ; Biological activity ; Biomedical and Life Sciences ; Biotechnology ; Drug discovery ; Endophytes ; Fungi ; Health aspects ; Herbal medicine ; Host plants ; Illnesses ; Life Sciences ; Medicinal plants ; Metabolites ; Microbial Genetics and Genomics ; Microbiology ; Microorganisms ; Mini-Review ; Natural products ; Plants (botany) ; Secondary metabolites ; Tabebuia</subject><ispartof>Applied microbiology and biotechnology, 2018-11, Vol.102 (21), p.9105-9119</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>COPYRIGHT 2018 Springer</rights><rights>Applied Microbiology and Biotechnology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c477t-153bf391c83a1438583de031c68ec65854ee8e5ae6e9b790b1aed440052a552c3</citedby><cites>FETCH-LOGICAL-c477t-153bf391c83a1438583de031c68ec65854ee8e5ae6e9b790b1aed440052a552c3</cites><orcidid>0000-0002-0448-5004</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00253-018-9344-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00253-018-9344-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30203146$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gómez, Omar Cabezas</creatorcontrib><creatorcontrib>Luiz, Jaine Honorata Hortolan</creatorcontrib><title>Endophytic fungi isolated from medicinal plants: future prospects of bioactive natural products from Tabebuia/Handroanthus endophytes</title><title>Applied microbiology and biotechnology</title><addtitle>Appl Microbiol Biotechnol</addtitle><addtitle>Appl Microbiol Biotechnol</addtitle><description>Medicinal plants are a rich source of natural products used to treat many diseases; therefore, they are the basis for a new drug discovery. Plants are capable of generating different bioactive secondary metabolites, but a large amount of botanical material is often necessary to obtain small amounts of the target substance. Nowadays, many medicinal plants are becoming rather scarce. For this reason, it is important to point out the interactions between endophytic microorganisms and the host plant, because endophytes are able to produce highly diverse compounds, including those from host plants that have important biological activities. Thence, this review aims at presenting the richness in bioactive compounds of the medicinal plants from
Tabebuia
and
Handroanthus
genera, as well as important aspects about endophyte-plant interactions, with emphasis on the production of bioactive compounds by endophytic fungi, which has been isolated from various medicinal plants for such a purpose. Furthermore, bio-prospection of natural products synthesized by endophytes isolated from the aforementioned genera used in traditional medicine could be used to treat illnesses.</description><subject>Bioactive compounds</subject><subject>Biological activity</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Drug discovery</subject><subject>Endophytes</subject><subject>Fungi</subject><subject>Health aspects</subject><subject>Herbal medicine</subject><subject>Host plants</subject><subject>Illnesses</subject><subject>Life Sciences</subject><subject>Medicinal plants</subject><subject>Metabolites</subject><subject>Microbial Genetics and Genomics</subject><subject>Microbiology</subject><subject>Microorganisms</subject><subject>Mini-Review</subject><subject>Natural products</subject><subject>Plants (botany)</subject><subject>Secondary 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Plants are capable of generating different bioactive secondary metabolites, but a large amount of botanical material is often necessary to obtain small amounts of the target substance. Nowadays, many medicinal plants are becoming rather scarce. For this reason, it is important to point out the interactions between endophytic microorganisms and the host plant, because endophytes are able to produce highly diverse compounds, including those from host plants that have important biological activities. Thence, this review aims at presenting the richness in bioactive compounds of the medicinal plants from
Tabebuia
and
Handroanthus
genera, as well as important aspects about endophyte-plant interactions, with emphasis on the production of bioactive compounds by endophytic fungi, which has been isolated from various medicinal plants for such a purpose. Furthermore, bio-prospection of natural products synthesized by endophytes isolated from the aforementioned genera used in traditional medicine could be used to treat illnesses.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>30203146</pmid><doi>10.1007/s00253-018-9344-3</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-0448-5004</orcidid></addata></record> |
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| ispartof | Applied microbiology and biotechnology, 2018-11, Vol.102 (21), p.9105-9119 |
| issn | 0175-7598 1432-0614 |
| language | eng |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Bioactive compounds Biological activity Biomedical and Life Sciences Biotechnology Drug discovery Endophytes Fungi Health aspects Herbal medicine Host plants Illnesses Life Sciences Medicinal plants Metabolites Microbial Genetics and Genomics Microbiology Microorganisms Mini-Review Natural products Plants (botany) Secondary metabolites Tabebuia |
| title | Endophytic fungi isolated from medicinal plants: future prospects of bioactive natural products from Tabebuia/Handroanthus endophytes |
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