Use of cationic microbubbles targeted to P-selectin to improve ultrasound-mediated gene transfection of hVEGF 165 to the ischemic myocardium

Gene therapies have been applied to the treatment of cardiovascular disease, but their use is limited by the need to deliver them to the right target. We have employed targeted contrast ultrasound-mediated gene transfection (TCUMGT) via ultrasound-targeted microbubble destruction (UTMD) to transfer...

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Veröffentlicht in:Journal of Zhejiang University. B. Science 2018-09, Vol.19 (9), p.699-707
Hauptverfasser: Shentu, Wei-Hui, Yan, Cao-Xin, Liu, Chun-Mei, Qi, Rui-Xiang, Wang, Yao, Huang, Zhao-Xu, Zhou, Li-Ming, You, Xiang-Dong
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Sprache:eng
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