Coronary Microvascular Smooth Muscle Cells Contribute to Heart Failure in Diabetes Mellitus by Increasing Methylglyoxal Flux

Prognosis for patients with type 1 diabetes mellitus (T1DM) who have heart failure is poor because of an incomplete understanding of molecular cues that trigger it and a lack of specific pharmacologic agents/strategies to slow/reverse its development. Supra-physiologic levels of the α-oxoaldehyde me...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2018-07, Vol.67 (Supplement_1)
1. Verfasser:	BIDASEE, KESHORE
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular disease Coronary vessels Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Endothelins Enzymes Fibrosis Gene transfer Heart diseases Heart failure Medical prognosis Microvasculature Myocytes Pyruvaldehyde Smooth muscle Streptozocin Tissues Ventricle
Online-Zugang:	Volltext
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