Potential therapeutic roles of 10-dehydrogingerdione and/or pentoxifylline against calcium deposition in aortic tissues of high dietary cholesterol-fed rabbits

The present study aimed to investigate the inhibitory effects of 10-dehydrogingerdione (10-DHGD) and pentoxifylline (PTX) either individually or in combined form on calcium deposition in high cholesterol diet (HCD)-fed rabbits as compared to atorvastatin (ATOR), and to clarify the underlying mechani...

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Veröffentlicht in:	Molecular and cellular biochemistry 2019-03, Vol.453 (1-2), p.131-142
Hauptverfasser:	Elseweidy, Mohamed M., Mohamed, Hoda E., Elrashidy, Rania A., Atteia, Hebatallah H., Elnagar, Gehad M., Ali, Abd El-Monem
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Aorta Arteriosclerosis Atherosclerosis Atorvastatin Attenuation Biochemistry Biocompatibility Biomedical and Life Sciences Biomedical materials Bone morphogenetic protein 2 Bone morphogenetic proteins Calcification Calcification (ectopic) Calcification (Physiology) Calcium Cardiology Cholesterol Comparative analysis Deposition Dyslipidemia Gene expression Health aspects High cholesterol diet High density lipoprotein Inflammation Lesions Life Sciences Medical Biochemistry Messenger RNA Metabolic disorders mRNA NF-κB protein Oncology Osteocalcin Osteopontin Osteoprotegerin Pentoxifylline Phosphatases Proteins Rabbits Rankings RNA
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