Electrochemical detection of intracellular glutathione based on ligand exchange assisted release of DNA-templated silver nanoparticles

•DNA sequences can be the template for AgNPs synthesis.•High-affinity binding of GSH and AgNPs can mediate ligand exchange reaction.•Dissolved AgNPs can arouse the ultra-sensitive electrochemical responses.•The method can specially monitor GSH in the serum samples and even Hela cells. Glutathione (G...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2017-06, Vol.244, p.151-156
Hauptverfasser:	Lv, Yun, Lu, Mengjia, Yang, Yucai, Yin, Yongmei, Zhao, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensors Deoxyribonucleic acid DNA DNA-templated AgNPs Electrochemical analysis Electrochemical detection Free radicals Glutathione Hela cells Ligand exchange Mass spectrometry Membranes Nanoparticles Proteins Silver
Online-Zugang:	Volltext
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