Different changes of the serum albumin cobalt-binding capacity induced by various oxidants
Impact of in vitro oxidative modification of the bovine serum albumin (BSA) on its cobaltbinding capacity (CoBC) was studied. We found various oxidants differently changed CoBC of BSA. The Fenton’s reagents producing hydroxyl radical decreased or not alter CoBC of BSA depending on composition of one...
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description | Impact of in vitro oxidative modification of the bovine serum albumin (BSA) on its cobaltbinding capacity (CoBC) was studied. We found various oxidants differently changed CoBC of BSA. The Fenton’s reagents producing hydroxyl radical decreased or not alter CoBC of BSA depending on composition of ones. In contrast, treatment of BSA by hypochlorous acid, a physiological oxidant, elevated CoBC of this protein. Probable causes of different effects produced by various oxidants is discussed. |
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subjects | Bovine serum albumin Cobalt Hydroxyl radicals Hypochlorous acid Oxidants Oxidation |
title | Different changes of the serum albumin cobalt-binding capacity induced by various oxidants |
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