Oxidative stress resistance: a robust correlated response to selection in extended longevity lines of Drosophila melanogaster?

Oxidative stress resistance: a robust correlated response to selection in extended longevity lines of Drosophila melanogaster?

Stress resistance is associated with longevity in Drosophila melanogaster and other model organisms used for genetic research. The present study tests for oxidative stress resistance in one set of lines selected for late-life reproduction and extended longevity. Both females and males from the selec...

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Veröffentlicht in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2000-09, Vol.55 (9), p.B415-B417
Hauptverfasser: Harshman, L G, Haberer, B A
Format: Artikel
Sprache:eng
Schlagworte:
Aging
Analysis of Variance
Animal reproduction
Animals
Drosophila melanogaster
Female
Genetics
Gerontology
Herbicides - adverse effects
Insects
Longevity - drug effects
Longevity - genetics
Male
Oxidative Stress - drug effects
Oxidative Stress - genetics
Oxidative Stress - physiology
Paraquat - adverse effects
Reproduction - genetics
Selection, Genetic
Survival Rate
Water
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container_end_page B417
container_issue 9
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container_title The journals of gerontology. Series A, Biological sciences and medical sciences
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creator Harshman, L G
Haberer, B A
description Stress resistance is associated with longevity in Drosophila melanogaster and other model organisms used for genetic research. The present study tests for oxidative stress resistance in one set of lines selected for late-life reproduction and extended longevity. Both females and males from the selected lines were appreciably more resistant to oxidative stress than were flies from the control lines. A relative increase in oxidative stress resistance is a correlated response to selection in this laboratory selection experiment. Increased oxidative stress resistance appears to be a relatively robust correlated response to laboratory selection for late-life reproduction and extended longevity.
doi_str_mv 10.1093/gerona/55.9.B415
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ispartof The journals of gerontology. Series A, Biological sciences and medical sciences, 2000-09, Vol.55 (9), p.B415-B417
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1758-535X
language eng
recordid cdi_proquest_journals_208629935
source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Periodicals Index Online
subjects Aging
Analysis of Variance
Animal reproduction
Animals
Drosophila melanogaster
Female
Genetics
Gerontology
Herbicides - adverse effects
Insects
Longevity - drug effects
Longevity - genetics
Male
Oxidative Stress - drug effects
Oxidative Stress - genetics
Oxidative Stress - physiology
Paraquat - adverse effects
Reproduction - genetics
Selection, Genetic
Survival Rate
Water
title Oxidative stress resistance: a robust correlated response to selection in extended longevity lines of Drosophila melanogaster?
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