Clostridium difficile toxins A and B decrease intestinal SLC26A3 protein expression

Clostridium difficile infection (CDI) is the primary cause of nosocomial diarrhea in the United States. Although C. difficile toxins A and B are the primary mediators of CDI, the overall pathophysiology underlying C. difficile-associated diarrhea remains poorly understood. Studies have shown that a...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2018-07, Vol.315 (1), p.307
Hauptverfasser:	Coffing, Hayley, Priyamvada, Shubha, Anbazhagan, Arivarasu N, Salibay, Christine, Engevik, Melinda, Versalovic, James, Yacyshyn, Mary Beth, Yacyshyn, Bruce, Tyagi, Sangeeta, Saksena, Seema, Gill, Ravinder K, Alrefai, Waddah A, Dudeja, Pradeep K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma Cell culture Clostridium difficile Diarrhea Electrolytes Epithelial cells Hospitals Infections Inflammation Intestine mRNA Na+/H+-exchanging ATPase Phenotypes Protein transport Toxins
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