Increased Endothelin-1 and Its Localization during the Development of Bleomycin-induced Pulmonary Fibrosis in Rats

Endothelin-1 (Et-1) has been implicated in the pathogenesis of pulmonary fibrosis with increased levels in the lung tissue of patients with pulmonary fibrosis and profibrotic effects in vitro. In this study we have investigated the temporal changes in lung Et-1 levels and immunohistochemical localiz...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 1998-05, Vol.18 (5), p.611-619
Hauptverfasser:	Mutsaers, Steven E, Foster, Martyn L, Chambers, Rachel C, Laurent, Geoffrey J, McAnulty, Robin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimetabolites, Antineoplastic Bleomycin Collagen - analysis Cross Reactions Endothelin-1 - analysis Endothelin-1 - immunology Endothelin-1 - metabolism Epithelial Cells - chemistry Epithelial Cells - metabolism Leukocytes - chemistry Leukocytes - metabolism Pulmonary Fibrosis - metabolism Pulmonary Fibrosis - pathology Rats Rats, Inbred Lew
Online-Zugang:	Volltext
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