High Levels of Peroxynitrite Are Generated in the Lungs of Irradiated Mice Given Cyclophosphamide and Allogeneic T Cells . A Potential Mechanism of Injury after Marrow Transplantation

In a murine bone-marrow transplant (BMT) model designed to determine risk factors for lung dysfunction in irradiated mice, we reported that cyclophosphamide (Cy)-induced injury and lethality depended on the infusion of donor spleen T cells. In the study reported here, we hypothesized that alveolar m...

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