Identification of Transforming Growth Factor {beta}1-Driven Genetic Programs of Acute Lung Fibrosis

Lung fibrosis is characterized by excessive accumulation of extracellular matrix components leading to progressive airflow limitation. Distinct profibrotic pathways converge on the activation of transforming growth factor-beta (TGF-beta), a central growth factor implicated in most fibroproliferative...

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Veröffentlicht in:American journal of respiratory cell and molecular biology 2008-09, Vol.39 (3), p.324
Hauptverfasser: Pulichino, Anne-Marie, Wang, I-Ming, Caron, Alexandre, Mortimer, James, Auger, Anick, Boie, Yves, Elias, Jack A, Kartono, Aileen, Xu, Lijing, Menetski, Joseph, Sayegh, Camil E
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Sprache:eng
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