Preclinical safety evaluation of the ethanolic extract from Campomanesia pubescens (Mart. ex DC.) O.BERG (guavira) fruits: analysis of genotoxicity and clastogenic effects

Genotoxicity studies of plants with medicinal and nutritional properties are recommended by international regulatory agencies as part of the risk assessment. Due to their consumption as food, nutraceutical use and ethnopharmacological relevance, Campomanesia pubescens represents one of these plants...

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Veröffentlicht in:	Food & function 2018-07, Vol.9 (7), p.3707-3717
Hauptverfasser:	Villas Boas, Gustavo Roberto, Souza de Araújo, Flávio Henrique, Moreira Marcelino, Jhony, Almeida Castro, Luis Henrique, Stefanello da Silveira, Ana Paula, Silva Nacer, Renato, Rodrigues de Souza, Fabio, Cardoso, Claudia Andréa Lima, Boerngen de Lacerda, Roseli, Guterres, Zaira da Rosa, Oesterreich, Silvia Aparecida
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioassays Biotransformation Bone marrow Comet assay Cytotoxicity Damage detection Drosophila melanogaster Flavonoids Food consumption Fruits Genotoxicity Larvae Liquidity Medicinal plants Metabolites Pulp Rats Regulatory agencies Risk assessment Toxicity
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