Hypoxic Depression of Pacemaker Activity of Interstitial Cells of Cajal: A Threat of Gastrointestinal Dysmotility and Necrosis. A Simulation Study

Hypoxic-ischemic injury is a known risk factor of necrotizing enterocolitis (NEC), an inflammatory bowel disease of neonates, one of the most common causes of intestinal failures associated with total bowel and/or segmental disorders of intestinal motility. The gastrointestinal motility is based, to...

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Veröffentlicht in:	Neurophysiology (New York) 2018-04, Vol.50 (2), p.76-82
Hauptverfasser:	Korogod, S. M., Cymbalyuk, G. S., Makedonsky, I. A., Kulagina, I. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Analysis ATPases Biomedical and Life Sciences Biomedicine Ca2+-transporting ATPase Calcium (intracellular) Calcium signalling Depolarization Electric currents Endoplasmic reticulum Enterocolitis Gastric motility Gastrointestinal diseases Hypoxia Inflammatory bowel diseases Interstitial cells Interstitial cells of Cajal Intestinal motility Intestine Ischemia Membrane potential Mental depression Mitochondria Motility Necrosis Necrotizing enterocolitis Neonates Neurosciences Pacemakers Plasma membranes Smooth muscle
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