A hypoxia-activated near infrared fluorescent probe for cyclooxygenase-2 and in vivo imaging for tumor and inflammation

[Display omitted] •A novel hypoxia-activated COX-2 specific fluorescent probe YZP1 was designed and synthesized.•Under hypoxia condition and the reduction of Cytochrome P450 reductase, a remarkable “off-on” fluorescence change was observed for YZP1 with the fluorescence quantum yield increasing from...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2018-07, Vol.265, p.582-590
Hauptverfasser:	Ti, Yuezheng, Yu, Ling, Tang, Yao, Jin, Tongxia, Yang, Ming, Wang, Rui, Xu, Yufang, Zhu, Weiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclooxygenase-2 Cytochrome Fluorescence Fluorescent dyes Fluorescent indicators Fluorescent probe Hypoxia Inflammation Medical imaging Tumor Tumors Xenotransplantation
Online-Zugang:	Volltext
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