One‐Pot Sequential Bromination and Fluorination to Access 3‐Fluoroimidazo[1,2‐a]pyridines from Arylketones

3‐Fluoro‐2‐arylimidazo[1,2‐a]pyridines were selectively synthesised in one‐pot from acetophenones and 2‐aminopyridines under mild conditions. The sequence of reactions involved bromination, condensation, and late‐stage fluorination. Two halogenating reagents play key roles in the process. We found t...

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Veröffentlicht in:	European journal of organic chemistry 2018-07, Vol.2018 (26), p.3432-3436
Hauptverfasser:	Udavant, Rohini N., Yadav, Ashok R., Shinde, Sandip S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bromination Bromine Condensates Cyclization Fluorination Fluorine Fused‐ring systems Halogenation Nitrogen heterocycles Pyridines Reagents
Online-Zugang:	Volltext
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