Fosmidomycin for malaria

Safe and effective antimalarial drugs with new methods of action are urgently needed. Fosmidomycin inhibits the synthesis of isoprenoid by Plasmodium falciparum, and suppresses the growth of multidrug-resistant strains in vitro. Our aim was to assess the efficacy and tolerability of fosmidomycin in...

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Veröffentlicht in:	The Lancet (British edition) 2002-12, Vol.360 (9349), p.1941-1942
Hauptverfasser:	Missinou, Michel A, Borrmann, Steffen, Schindler, Andreas, Issifou, Saadou, Adegnika, Ayola A, Matsiegui, Pierre-Blaise, Binder, Ronald, Lell, Bertrand, Wiesner, Jochen, Baranek, Thomas, Jomaa, Hassan, Kremsner, Peter G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Animals Biological and medical sciences Clinical trials Drug Administration Schedule Drug resistance Drug therapy Female Fever Fosfomycin - administration & dosage Fosfomycin - adverse effects Fosfomycin - analogs & derivatives Fosfomycin - therapeutic use Fosmidomycin Gabon Human protozoal diseases Humans Infectious diseases Malaria Malaria, Falciparum - drug therapy Male Medical research Medical sciences Multidrug resistance Pain Parasites Parasitic diseases Patients Plasmodium falciparum Plasmodium falciparum - drug effects Protozoal diseases Schweitzer, Albert Treatment Outcome Tropical medicine Vector-borne diseases
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