Hydrogels with novel hydrolytically labile trehalose-based crosslinks: small changes - big differences in degradation behavior

Novel crosslinkers based on trehalose diacetals with acryloyloxy functionalities were synthesized and applied to the fabrication of degradable hydrogels with pH-dependent degradation characteristics at around physiological pH. Degradability at pH < 7 was ensured by the acetal group, while degrada...

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Veröffentlicht in:	Polymer chemistry 2018-07, Vol.9 (27), p.3721-3726
Hauptverfasser:	Burek, Ma gorzata, Wa kiewicz, Sylwia, Lalik, Anna, Wandzik, Ilona
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamide Cleavage Crosslinking Degradation Hydrogels NMR spectroscopy Polymer chemistry Trehalose
Online-Zugang:	Volltext
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