Cerebral clearance of human amyloid-[beta] peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes

Soluble amyloid-[beta] peptide (A[beta]) exists in the form of monomers and oligomers, and as complexes with A[beta]-binding molecules, such as low-density lipoprotein receptor-related protein-1 (LRP-1) ligands. The present study investigated the effect of self-aggregation and LRP-1 ligands on the e...

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Veröffentlicht in:	Journal of neurochemistry 2007-12, Vol.103 (6), p.2482
Hauptverfasser:	Ito, Shingo, Ohtsuki, Sumio, Kamiie, Junichi, Nezu, Yasuko, Terasaki, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Brain Molecular biology Neurology Peptides Rodents
Online-Zugang:	Volltext
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