Cytotoxic Effect of Some Digitalis Species; A Study of Selectivity

Cell Lines HeLa (human cervix epithelial cancer cell) cell line was provided by Prof. Dr. Nursen Basaran's cell line collection (Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara), 3Y1 (rat fibroblast cell) cell were provided by the Health Science Research Resources Bank (Osaka, Japan). According to these results, cells were neither dying nor growing due to cytostatic activity. [...]according to our cytotoxicity studies on some Digitalis species, the extracts showed selective cytotoxicity on the tested cancer and noncancerous cell lines. [...]the selectivity was also seen between different cancer cell lines. (2005), Effects of phenylethanoid glycosides from Digitalis purpurea L. on the expression of inducible nitric oxide synthase, Journal of Pharmacy and Pharmacology, 57 (7), 903-910.