A novel signal amplification system fabricated immunosensor based on Au nanoparticles and mesoporous trimetallic PdPtCu nanospheres for sensitive detection of prostate specific antigen

•The m-PdPtCu was first used as the label of secondary antibodies in immunosensor.•The m-PdPtCu showed an excellent performance in signal amplification.•The immunosensor enabled highly sensitive and selective detection of PSA.•The designed immunosensor is promising in early clinical diagnosis of bio...

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