Polymorphic Variants of Immune Response Genes as a Risk Factor for the Development of Primary Progressive Multiple Sclerosis

Objectives. To analyze the involvement of immune response genes in the pathogenesis of primary progressive multiple sclerosis (PPMS). Materials and methods. A representative cohort of 111 ethnically Russian patients with PPMS took part in a multicenter study. The involvement of immune system genes i...

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Veröffentlicht in:	Neuroscience and behavioral physiology 2018-07, Vol.48 (6), p.661-667
Hauptverfasser:	Popova, E. V., Kiselev, I. S., Boiko, A. N., Sivertseva, S. A., Malkova, N. A., Korobko, D. S., Spirin, N. N., Kasatkin, D. S., Karaeva, A. V., Turova, E. L., Spirina, N. N., Volkova, L. I., Baulina, N. M., Bashinskaya, V. V., Kulakova, O. G., Favorova, O. O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen presentation Antigen processing Antigen-presenting cells Antigens Behavioral Sciences Biomedical and Life Sciences Biomedicine Drb1 protein Genotypes Histocompatibility antigen HLA Immune response Interleukin 4 Multiple sclerosis Neurobiology Neurosciences Pathogenesis Population studies Risk factors
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