EFFECT OF THE YACON (SMALLANTHUS SONCHIFOLIUS) IN GLYCEMIC PROFILE OF THE WISTAR RATS
Background and objectives: Yacon is considered a functional food, which has among its properties a hypoglycemic capacity. The aim of this study was to evaluate the modulatory effect of yacon in the glycemic profile of Wistar rats. Methods: The experiment lasted 60 days with 32 animals. It was used t...
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Veröffentlicht in: | Annals of nutrition and metabolism 2017-10, Vol.71 (Suppl. 2), p.479 |
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creator | Vasconcelos, Debora e Silva, Thaiany Goulart de Souza Costa, Lellis Henrique Paula, Hudsara Aparecida Almeida |
description | Background and objectives: Yacon is considered a functional food, which has among its properties a hypoglycemic capacity. The aim of this study was to evaluate the modulatory effect of yacon in the glycemic profile of Wistar rats. Methods: The experiment lasted 60 days with 32 animals. It was used the dehydrated food matrix (yacon powder / YP) added to the diet of the groups that received intervention in the dose of 7.5% of inulin type fructan (ITF). The analyzed variables were: centesimal composition and content of inulin type frutans, weight gain, relative weight of cecum (RWC), food consumption, coefficient of food efficiency and glycemia. All analyzes followed the AOAC protocols. In the statistical analysis, the following tests were used: ANOVA or Kruskal Wallis followed by comparison tests of means, t test and paired t test. The level of statistical significance was p |
doi_str_mv | 10.1159/000480486 |
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The aim of this study was to evaluate the modulatory effect of yacon in the glycemic profile of Wistar rats. Methods: The experiment lasted 60 days with 32 animals. It was used the dehydrated food matrix (yacon powder / YP) added to the diet of the groups that received intervention in the dose of 7.5% of inulin type fructan (ITF). The analyzed variables were: centesimal composition and content of inulin type frutans, weight gain, relative weight of cecum (RWC), food consumption, coefficient of food efficiency and glycemia. All analyzes followed the AOAC protocols. In the statistical analysis, the following tests were used: ANOVA or Kruskal Wallis followed by comparison tests of means, t test and paired t test. The level of statistical significance was p <0.05 for all analyzes. This study was approved by the Ethics Committee on the Use of Animals of the Federal University of Alfenas, protocol no. 698/2015. Results: The results showed that the control group receiving YP had a significant reduction in glycemic values. In all groups receiving YP there was a significant increase of cecum, as expected. The development of diabetes was not observed due to the use of streptozotocin with 35% sucrose. Conclusions: Therefore, the evaluation of the effect of yacon on hypoglycaemia has been impaired. This suggests that studies in this line are encouraged for further elucidations.</description><identifier>ISSN: 0250-6807</identifier><identifier>EISSN: 1421-9697</identifier><identifier>DOI: 10.1159/000480486</identifier><language>eng</language><publisher>Basel: S. Karger AG</publisher><subject>Animals ; Blood glucose ; Cecum ; Crops ; Dehydrated food ; Dehydration ; Diabetes mellitus ; Ethical standards ; Food ; Food consumption ; Food matrix ; Functional foods & nutraceuticals ; Hypoglycemia ; Inulin ; Powder ; Rats ; Rodents ; Statistical analysis ; Streptozocin ; Sucrose ; Sugar ; Variance analysis</subject><ispartof>Annals of nutrition and metabolism, 2017-10, Vol.71 (Suppl. 2), p.479</ispartof><rights>Copyright S. Karger AG Oct 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27928,27929</link.rule.ids></links><search><creatorcontrib>Vasconcelos, Debora</creatorcontrib><creatorcontrib>e Silva, Thaiany Goulart de Souza</creatorcontrib><creatorcontrib>Costa, Lellis Henrique</creatorcontrib><creatorcontrib>Paula, Hudsara Aparecida Almeida</creatorcontrib><title>EFFECT OF THE YACON (SMALLANTHUS SONCHIFOLIUS) IN GLYCEMIC PROFILE OF THE WISTAR RATS</title><title>Annals of nutrition and metabolism</title><description>Background and objectives: Yacon is considered a functional food, which has among its properties a hypoglycemic capacity. The aim of this study was to evaluate the modulatory effect of yacon in the glycemic profile of Wistar rats. Methods: The experiment lasted 60 days with 32 animals. It was used the dehydrated food matrix (yacon powder / YP) added to the diet of the groups that received intervention in the dose of 7.5% of inulin type fructan (ITF). The analyzed variables were: centesimal composition and content of inulin type frutans, weight gain, relative weight of cecum (RWC), food consumption, coefficient of food efficiency and glycemia. All analyzes followed the AOAC protocols. In the statistical analysis, the following tests were used: ANOVA or Kruskal Wallis followed by comparison tests of means, t test and paired t test. The level of statistical significance was p <0.05 for all analyzes. This study was approved by the Ethics Committee on the Use of Animals of the Federal University of Alfenas, protocol no. 698/2015. Results: The results showed that the control group receiving YP had a significant reduction in glycemic values. In all groups receiving YP there was a significant increase of cecum, as expected. The development of diabetes was not observed due to the use of streptozotocin with 35% sucrose. Conclusions: Therefore, the evaluation of the effect of yacon on hypoglycaemia has been impaired. This suggests that studies in this line are encouraged for further elucidations.</description><subject>Animals</subject><subject>Blood glucose</subject><subject>Cecum</subject><subject>Crops</subject><subject>Dehydrated food</subject><subject>Dehydration</subject><subject>Diabetes mellitus</subject><subject>Ethical standards</subject><subject>Food</subject><subject>Food consumption</subject><subject>Food matrix</subject><subject>Functional foods & nutraceuticals</subject><subject>Hypoglycemia</subject><subject>Inulin</subject><subject>Powder</subject><subject>Rats</subject><subject>Rodents</subject><subject>Statistical analysis</subject><subject>Streptozocin</subject><subject>Sucrose</subject><subject>Sugar</subject><subject>Variance analysis</subject><issn>0250-6807</issn><issn>1421-9697</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqNiz2rwjAYRoNcwV518B-84KJD9U1tYzOGkNwG0kaaFHESBx1E_Kr-fx10v_DAGc55CBlRnFGa8Tkipvl7rEMimiY05owvf0iESYYxy3HZI79te0SkSZ5mEWmU1koGcBpCoWAjpKtg4kthrahC0XjwrpKF0c6axk_BVPBnN1KVRsKqdtpY9f2ujQ-ihloEPyDdw-7U7ocf9slYqyCL-Hq_3J779rE9Xp7381ttE2Q055yzxeJ_1QsuPDzH</recordid><startdate>20171001</startdate><enddate>20171001</enddate><creator>Vasconcelos, Debora</creator><creator>e Silva, Thaiany Goulart de Souza</creator><creator>Costa, Lellis Henrique</creator><creator>Paula, Hudsara Aparecida Almeida</creator><general>S. Karger AG</general><scope>7QP</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20171001</creationdate><title>EFFECT OF THE YACON (SMALLANTHUS SONCHIFOLIUS) IN GLYCEMIC PROFILE OF THE WISTAR RATS</title><author>Vasconcelos, Debora ; e Silva, Thaiany Goulart de Souza ; Costa, Lellis Henrique ; Paula, Hudsara Aparecida Almeida</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_20618999633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Blood glucose</topic><topic>Cecum</topic><topic>Crops</topic><topic>Dehydrated food</topic><topic>Dehydration</topic><topic>Diabetes mellitus</topic><topic>Ethical standards</topic><topic>Food</topic><topic>Food consumption</topic><topic>Food matrix</topic><topic>Functional foods & nutraceuticals</topic><topic>Hypoglycemia</topic><topic>Inulin</topic><topic>Powder</topic><topic>Rats</topic><topic>Rodents</topic><topic>Statistical analysis</topic><topic>Streptozocin</topic><topic>Sucrose</topic><topic>Sugar</topic><topic>Variance analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vasconcelos, Debora</creatorcontrib><creatorcontrib>e Silva, Thaiany Goulart de Souza</creatorcontrib><creatorcontrib>Costa, Lellis Henrique</creatorcontrib><creatorcontrib>Paula, Hudsara Aparecida Almeida</creatorcontrib><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Annals of nutrition and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vasconcelos, Debora</au><au>e Silva, Thaiany Goulart de Souza</au><au>Costa, Lellis Henrique</au><au>Paula, Hudsara Aparecida Almeida</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>EFFECT OF THE YACON (SMALLANTHUS SONCHIFOLIUS) IN GLYCEMIC PROFILE OF THE WISTAR RATS</atitle><jtitle>Annals of nutrition and metabolism</jtitle><date>2017-10-01</date><risdate>2017</risdate><volume>71</volume><issue>Suppl. 2</issue><spage>479</spage><pages>479-</pages><issn>0250-6807</issn><eissn>1421-9697</eissn><abstract>Background and objectives: Yacon is considered a functional food, which has among its properties a hypoglycemic capacity. The aim of this study was to evaluate the modulatory effect of yacon in the glycemic profile of Wistar rats. Methods: The experiment lasted 60 days with 32 animals. It was used the dehydrated food matrix (yacon powder / YP) added to the diet of the groups that received intervention in the dose of 7.5% of inulin type fructan (ITF). The analyzed variables were: centesimal composition and content of inulin type frutans, weight gain, relative weight of cecum (RWC), food consumption, coefficient of food efficiency and glycemia. All analyzes followed the AOAC protocols. In the statistical analysis, the following tests were used: ANOVA or Kruskal Wallis followed by comparison tests of means, t test and paired t test. The level of statistical significance was p <0.05 for all analyzes. This study was approved by the Ethics Committee on the Use of Animals of the Federal University of Alfenas, protocol no. 698/2015. Results: The results showed that the control group receiving YP had a significant reduction in glycemic values. In all groups receiving YP there was a significant increase of cecum, as expected. The development of diabetes was not observed due to the use of streptozotocin with 35% sucrose. Conclusions: Therefore, the evaluation of the effect of yacon on hypoglycaemia has been impaired. This suggests that studies in this line are encouraged for further elucidations.</abstract><cop>Basel</cop><pub>S. Karger AG</pub><doi>10.1159/000480486</doi></addata></record> |
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subjects | Animals Blood glucose Cecum Crops Dehydrated food Dehydration Diabetes mellitus Ethical standards Food Food consumption Food matrix Functional foods & nutraceuticals Hypoglycemia Inulin Powder Rats Rodents Statistical analysis Streptozocin Sucrose Sugar Variance analysis |
title | EFFECT OF THE YACON (SMALLANTHUS SONCHIFOLIUS) IN GLYCEMIC PROFILE OF THE WISTAR RATS |
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