Spatial and environmental correlates of organism colonization and infection in the neonatal intensive care unit
Objective To examine organism colonization and infection in the neonatal intensive care unit as a result of environmental and spatial factors. Study design A retrospective cohort of infants admitted between 2006 and 2015 ( n = 11 428), to assess the relationship between location and four outcomes:...
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Veröffentlicht in: | Journal of perinatology 2018-05, Vol.38 (5), p.567-573 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
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Zusammenfassung: | Objective
To examine organism colonization and infection in the neonatal intensive care unit as a result of environmental and spatial factors.
Study design
A retrospective cohort of infants admitted between 2006 and 2015 (
n
= 11 428), to assess the relationship between location and four outcomes: methicillin-resistant
Staphylococcus aureus
(MRSA) colonization; culture-confirmed late-onset sepsis; and, if intubated, endotracheal tube colonization with
Pseudomonas aeruginosa
or
Klebsiella pneumonia
. Independent risk factors were identified with mixed-effects logistic regression models and Moran’s
I
for spatial autocorrelation.
Result
All four outcomes statistically clustered by location; neighboring colonization also influenced risk of MRSA (
p
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ISSN: | 0743-8346 1476-5543 |
DOI: | 10.1038/s41372-017-0019-1 |