Spatial and environmental correlates of organism colonization and infection in the neonatal intensive care unit

Objective To examine organism colonization and infection in the neonatal intensive care unit as a result of environmental and spatial factors. Study design A retrospective cohort of infants admitted between 2006 and 2015 ( n  = 11 428), to assess the relationship between location and four outcomes:...

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Veröffentlicht in:Journal of perinatology 2018-05, Vol.38 (5), p.567-573
Hauptverfasser: Goldstein, Neal D., Tuttle, Deborah, Tabb, Loni P., Paul, David A., Eppes, Stephen C.
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Sprache:eng
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Zusammenfassung:Objective To examine organism colonization and infection in the neonatal intensive care unit as a result of environmental and spatial factors. Study design A retrospective cohort of infants admitted between 2006 and 2015 ( n  = 11 428), to assess the relationship between location and four outcomes: methicillin-resistant Staphylococcus aureus (MRSA) colonization; culture-confirmed late-onset sepsis; and, if intubated, endotracheal tube colonization with Pseudomonas aeruginosa or Klebsiella pneumonia . Independent risk factors were identified with mixed-effects logistic regression models and Moran’s I for spatial autocorrelation. Result All four outcomes statistically clustered by location; neighboring colonization also influenced risk of MRSA ( p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-017-0019-1