CC Chemokine Receptor 2 Is Required for Macrophage Infiltration and Vascular Hypertrophy in Angiotensin II–Induced Hypertension

Recent studies have identified the presence of macrophages in the arterial wall of hypertensive animals and suggested that as is the case in atherosclerosis, macrophage products may be important mediators of the adaptive response of the arterial wall. In support of this, we have previously shown tha...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2000-09, Vol.36 (3), p.360-363
Hauptverfasser:	Bush, Errol, Maeda, Nobuyo, Kuziel, William A, Dawson, Tracey C, Wilcox, Josiah N, DeLeon, Hector, Taylor, W Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Animals Aorta, Thoracic - pathology Arterial hypertension. Arterial hypotension Biological and medical sciences Biomarkers - analysis Blood and lymphatic vessels Cardiology. Vascular system Cell Movement Endothelium, Vascular - pathology Experimental diseases Hypertension - chemically induced Hypertension - pathology Hypertrophy - pathology Macrophages - chemistry Macrophages - physiology Medical sciences Mice Mice, Inbred C57BL Receptor, Macrophage Colony-Stimulating Factor - analysis Receptors, CCR2 Receptors, Chemokine - deficiency Receptors, Chemokine - physiology Vasculitis - etiology Vasculitis - pathology Vasoconstrictor Agents
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