Use of a charged lidocaine derivative, tonicaine, for prolonged infiltration anesthesia

Background and Objectives: We tested the hypothesis that the duration of cutaneous anesthesia elicited by the permanently charged compound N-phenylethyl lidocaine (tonicaine) would be longer than that elicited by its parent structure, lidocaine, and that it would be less affected by epinephrine (epi...

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Veröffentlicht in:	Regional anesthesia and pain medicine 2002-03, Vol.27 (2), p.173-179
Hauptverfasser:	Khan, Mohammed A., Gerner, Peter, Sudoh, Yukari, Wang, Ging Kuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia, Local Anesthetics, Local - pharmacology Animals Lidocaine - adverse effects Lidocaine - analogs & derivatives Lidocaine - pharmacology Male Rats Rats, Sprague-Dawley Regional anesthesia Skin - drug effects Time Factors
Online-Zugang:	Volltext
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