Favorable binding of Quercetin to á-Synuclein as potential target in Parkinson disease: An Insilico approach

[...]there is loss of dopamine production leading to severe motor symptoms. [...]the .pdbqtfile of the protein is employed for our docking experiment.] 2.4 Identification of binding site residues: [...]quercetin had shown the favorable binding with a-synuclein. asynuclein was the main target for PD as it initiates various other processes leading to cell death. [...]up-regulating Hsp7018 and activating lysosomal degradation19 are also the potential targets for reducing a-synuclein aggregation.