Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients
Background Ventilation‐weighted Fourier decomposition‐MRI (FD‐MRI) has matured as a reliable technique for quantitative measures of regional lung ventilation in recent years, but has yet not been validated in COPD patients. Purpose/Hypothesis To compare regional fractional lung ventilation obtained...
Gespeichert in:
| Veröffentlicht in: | Journal of magnetic resonance imaging 2018-06, Vol.47 (6), p.1534-1541 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1541 |
|---|---|
| container_issue | 6 |
| container_start_page | 1534 |
| container_title | Journal of magnetic resonance imaging |
| container_volume | 47 |
| creator | Kaireit, Till F. Gutberlet, Marcel Voskrebenzev, Andreas Freise, Julia Welte, Tobias Hohlfeld, Jens M. Wacker, Frank Vogel‐Claussen, Jens |
| description | Background
Ventilation‐weighted Fourier decomposition‐MRI (FD‐MRI) has matured as a reliable technique for quantitative measures of regional lung ventilation in recent years, but has yet not been validated in COPD patients.
Purpose/Hypothesis
To compare regional fractional lung ventilation obtained by ventilation‐weighted FD‐MRI with dynamic fluorinated gas washout MRI (19F‐MRI) and lung function test parameters.
Study Type
Prospective study.
Population
Twenty‐seven patients with chronic obstructive pulmonary disease (COPD, median age 61 [54–67] years) were included.
Field Strength/Sequence
For FD‐MRI and for 19F‐MRI a spoiled gradient echo sequence was used at 1.5T.
Assessment
FD‐MRI coronal slices were acquired in free breathing. Dynamic 19F‐MRI was performed after inhalation of 25–30 L of a mixture of 79% fluorinated gas (C3F8) and 21% oxygen via a closed face mask tubing using a dedicated coil tuned to 59.9 MHz. 19F washout times in numbers of breaths (19F‐nbreaths) as well as fractional ventilation maps for both methods (FD‐FV, 19F‐FV) were calculated. Slices were matched using a landmark driven algorithm, and only corresponding slices with an overlap of >90% were coregistered for evaluation.
Statistical Tests
The obtained parameters were correlated with each other using Spearman's correlation coefficient (r).
Results
FD‐FV strongly correlated with 19F‐nbreaths on a global (r = –0.72, P < 0.0001) as well as on a lobar level and with lung function test parameters (FD‐FV vs. FEV1, r = 0.76, P < 0.0001). There was a small systematic overestimation of FD‐FV compared to 19F‐FV (mean difference –0.03 (95% confidence interval [CI]: –0.097; –0.045).
Data Conclusion
Regional ventilation‐weighted Fourier decomposition‐MRI is a promising noninvasive, radiation‐free tool for quantification of regional ventilation in COPD patients.
Level of Evidence: 2
Technical Efficacy: Stage 2
J. Magn. Reson. Imaging 2018;47:1534–1541. |
| doi_str_mv | 10.1002/jmri.25902 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2047425757</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2047425757</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3572-65355a4892c466a6ee96af0c2c55279c1ecfb4f0a022bc37d779c85fea0801aa3</originalsourceid><addsrcrecordid>eNp9kc1OGzEUhS0EAkrZ8ACVJXZIA9ee8fwsUVraoKCgql2Pbjx24mjGDvZMouz6CH2MPlefpE5CWbKydfSdc-17CLlicMsA-N2y8-aWiwr4ETlngvOEizI_jncQacJKKM7IhxCWAFBVmTglZ7xieXTCOfkzct0KvQnOUqfpy4C2Nz32Zq2oV3PjLLZ0raLYRtHZv79-b5SZL3rVUO0Gb5SnjZIxxAWzA-jT9zHdmH5Bm63Fzkiq28F5Y3FnmWOgGwwLN_R7EG1D28HOqR6s3Nt7FXoTBWPpaPr8ma7i2Dg-fCQnGtugLl_PC_Lz4cuP0bdkMv06Ht1PEpmKgie5SIXArKy4zPIcc6WqHDVILoXgRSWZknqWaUDgfCbToimiWAqtEEpgiOkFuT7krrx7GeJj6mX8ZtxCqDlkRcZFIYpI3Rwo6V0IXul65U2HflszqHel1LtS6n0pEf70GjnMOtW8of9biAA7ABvTqu07UfVjXNoh9B9q4Zw9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2047425757</pqid></control><display><type>article</type><title>Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients</title><source>Wiley Free Content</source><source>Wiley Online Library All Journals</source><creator>Kaireit, Till F. ; Gutberlet, Marcel ; Voskrebenzev, Andreas ; Freise, Julia ; Welte, Tobias ; Hohlfeld, Jens M. ; Wacker, Frank ; Vogel‐Claussen, Jens</creator><creatorcontrib>Kaireit, Till F. ; Gutberlet, Marcel ; Voskrebenzev, Andreas ; Freise, Julia ; Welte, Tobias ; Hohlfeld, Jens M. ; Wacker, Frank ; Vogel‐Claussen, Jens</creatorcontrib><description>Background
Ventilation‐weighted Fourier decomposition‐MRI (FD‐MRI) has matured as a reliable technique for quantitative measures of regional lung ventilation in recent years, but has yet not been validated in COPD patients.
Purpose/Hypothesis
To compare regional fractional lung ventilation obtained by ventilation‐weighted FD‐MRI with dynamic fluorinated gas washout MRI (19F‐MRI) and lung function test parameters.
Study Type
Prospective study.
Population
Twenty‐seven patients with chronic obstructive pulmonary disease (COPD, median age 61 [54–67] years) were included.
Field Strength/Sequence
For FD‐MRI and for 19F‐MRI a spoiled gradient echo sequence was used at 1.5T.
Assessment
FD‐MRI coronal slices were acquired in free breathing. Dynamic 19F‐MRI was performed after inhalation of 25–30 L of a mixture of 79% fluorinated gas (C3F8) and 21% oxygen via a closed face mask tubing using a dedicated coil tuned to 59.9 MHz. 19F washout times in numbers of breaths (19F‐nbreaths) as well as fractional ventilation maps for both methods (FD‐FV, 19F‐FV) were calculated. Slices were matched using a landmark driven algorithm, and only corresponding slices with an overlap of >90% were coregistered for evaluation.
Statistical Tests
The obtained parameters were correlated with each other using Spearman's correlation coefficient (r).
Results
FD‐FV strongly correlated with 19F‐nbreaths on a global (r = –0.72, P < 0.0001) as well as on a lobar level and with lung function test parameters (FD‐FV vs. FEV1, r = 0.76, P < 0.0001). There was a small systematic overestimation of FD‐FV compared to 19F‐FV (mean difference –0.03 (95% confidence interval [CI]: –0.097; –0.045).
Data Conclusion
Regional ventilation‐weighted Fourier decomposition‐MRI is a promising noninvasive, radiation‐free tool for quantification of regional ventilation in COPD patients.
Level of Evidence: 2
Technical Efficacy: Stage 2
J. Magn. Reson. Imaging 2018;47:1534–1541.</description><identifier>ISSN: 1053-1807</identifier><identifier>EISSN: 1522-2586</identifier><identifier>DOI: 10.1002/jmri.25902</identifier><identifier>PMID: 29160020</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>19F ; Breathing ; Chronic obstructive pulmonary disease ; Confidence intervals ; COPD ; Correlation coefficient ; Correlation coefficients ; Decomposition ; Field strength ; Fluorination ; Fourier decomposition ; free breathing ; Inhalation ; Lung diseases ; lung function tests ; Magnetic resonance imaging ; Mathematical analysis ; Obstructive lung disease ; Parameters ; Patients ; Population (statistical) ; Population studies ; Protective equipment ; Radiation ; Respiration ; Respiratory function ; Statistical analysis ; Statistical tests ; Ventilation ; washout</subject><ispartof>Journal of magnetic resonance imaging, 2018-06, Vol.47 (6), p.1534-1541</ispartof><rights>2017 International Society for Magnetic Resonance in Medicine</rights><rights>2017 International Society for Magnetic Resonance in Medicine.</rights><rights>2018 International Society for Magnetic Resonance in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3572-65355a4892c466a6ee96af0c2c55279c1ecfb4f0a022bc37d779c85fea0801aa3</citedby><cites>FETCH-LOGICAL-c3572-65355a4892c466a6ee96af0c2c55279c1ecfb4f0a022bc37d779c85fea0801aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmri.25902$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmri.25902$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27923,27924,45573,45574,46408,46832</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29160020$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kaireit, Till F.</creatorcontrib><creatorcontrib>Gutberlet, Marcel</creatorcontrib><creatorcontrib>Voskrebenzev, Andreas</creatorcontrib><creatorcontrib>Freise, Julia</creatorcontrib><creatorcontrib>Welte, Tobias</creatorcontrib><creatorcontrib>Hohlfeld, Jens M.</creatorcontrib><creatorcontrib>Wacker, Frank</creatorcontrib><creatorcontrib>Vogel‐Claussen, Jens</creatorcontrib><title>Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients</title><title>Journal of magnetic resonance imaging</title><addtitle>J Magn Reson Imaging</addtitle><description>Background
Ventilation‐weighted Fourier decomposition‐MRI (FD‐MRI) has matured as a reliable technique for quantitative measures of regional lung ventilation in recent years, but has yet not been validated in COPD patients.
Purpose/Hypothesis
To compare regional fractional lung ventilation obtained by ventilation‐weighted FD‐MRI with dynamic fluorinated gas washout MRI (19F‐MRI) and lung function test parameters.
Study Type
Prospective study.
Population
Twenty‐seven patients with chronic obstructive pulmonary disease (COPD, median age 61 [54–67] years) were included.
Field Strength/Sequence
For FD‐MRI and for 19F‐MRI a spoiled gradient echo sequence was used at 1.5T.
Assessment
FD‐MRI coronal slices were acquired in free breathing. Dynamic 19F‐MRI was performed after inhalation of 25–30 L of a mixture of 79% fluorinated gas (C3F8) and 21% oxygen via a closed face mask tubing using a dedicated coil tuned to 59.9 MHz. 19F washout times in numbers of breaths (19F‐nbreaths) as well as fractional ventilation maps for both methods (FD‐FV, 19F‐FV) were calculated. Slices were matched using a landmark driven algorithm, and only corresponding slices with an overlap of >90% were coregistered for evaluation.
Statistical Tests
The obtained parameters were correlated with each other using Spearman's correlation coefficient (r).
Results
FD‐FV strongly correlated with 19F‐nbreaths on a global (r = –0.72, P < 0.0001) as well as on a lobar level and with lung function test parameters (FD‐FV vs. FEV1, r = 0.76, P < 0.0001). There was a small systematic overestimation of FD‐FV compared to 19F‐FV (mean difference –0.03 (95% confidence interval [CI]: –0.097; –0.045).
Data Conclusion
Regional ventilation‐weighted Fourier decomposition‐MRI is a promising noninvasive, radiation‐free tool for quantification of regional ventilation in COPD patients.
Level of Evidence: 2
Technical Efficacy: Stage 2
J. Magn. Reson. Imaging 2018;47:1534–1541.</description><subject>19F</subject><subject>Breathing</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Confidence intervals</subject><subject>COPD</subject><subject>Correlation coefficient</subject><subject>Correlation coefficients</subject><subject>Decomposition</subject><subject>Field strength</subject><subject>Fluorination</subject><subject>Fourier decomposition</subject><subject>free breathing</subject><subject>Inhalation</subject><subject>Lung diseases</subject><subject>lung function tests</subject><subject>Magnetic resonance imaging</subject><subject>Mathematical analysis</subject><subject>Obstructive lung disease</subject><subject>Parameters</subject><subject>Patients</subject><subject>Population (statistical)</subject><subject>Population studies</subject><subject>Protective equipment</subject><subject>Radiation</subject><subject>Respiration</subject><subject>Respiratory function</subject><subject>Statistical analysis</subject><subject>Statistical tests</subject><subject>Ventilation</subject><subject>washout</subject><issn>1053-1807</issn><issn>1522-2586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kc1OGzEUhS0EAkrZ8ACVJXZIA9ee8fwsUVraoKCgql2Pbjx24mjGDvZMouz6CH2MPlefpE5CWbKydfSdc-17CLlicMsA-N2y8-aWiwr4ETlngvOEizI_jncQacJKKM7IhxCWAFBVmTglZ7xieXTCOfkzct0KvQnOUqfpy4C2Nz32Zq2oV3PjLLZ0raLYRtHZv79-b5SZL3rVUO0Gb5SnjZIxxAWzA-jT9zHdmH5Bm63Fzkiq28F5Y3FnmWOgGwwLN_R7EG1D28HOqR6s3Nt7FXoTBWPpaPr8ma7i2Dg-fCQnGtugLl_PC_Lz4cuP0bdkMv06Ht1PEpmKgie5SIXArKy4zPIcc6WqHDVILoXgRSWZknqWaUDgfCbToimiWAqtEEpgiOkFuT7krrx7GeJj6mX8ZtxCqDlkRcZFIYpI3Rwo6V0IXul65U2HflszqHel1LtS6n0pEf70GjnMOtW8of9biAA7ABvTqu07UfVjXNoh9B9q4Zw9</recordid><startdate>201806</startdate><enddate>201806</enddate><creator>Kaireit, Till F.</creator><creator>Gutberlet, Marcel</creator><creator>Voskrebenzev, Andreas</creator><creator>Freise, Julia</creator><creator>Welte, Tobias</creator><creator>Hohlfeld, Jens M.</creator><creator>Wacker, Frank</creator><creator>Vogel‐Claussen, Jens</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope></search><sort><creationdate>201806</creationdate><title>Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients</title><author>Kaireit, Till F. ; Gutberlet, Marcel ; Voskrebenzev, Andreas ; Freise, Julia ; Welte, Tobias ; Hohlfeld, Jens M. ; Wacker, Frank ; Vogel‐Claussen, Jens</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3572-65355a4892c466a6ee96af0c2c55279c1ecfb4f0a022bc37d779c85fea0801aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>19F</topic><topic>Breathing</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Confidence intervals</topic><topic>COPD</topic><topic>Correlation coefficient</topic><topic>Correlation coefficients</topic><topic>Decomposition</topic><topic>Field strength</topic><topic>Fluorination</topic><topic>Fourier decomposition</topic><topic>free breathing</topic><topic>Inhalation</topic><topic>Lung diseases</topic><topic>lung function tests</topic><topic>Magnetic resonance imaging</topic><topic>Mathematical analysis</topic><topic>Obstructive lung disease</topic><topic>Parameters</topic><topic>Patients</topic><topic>Population (statistical)</topic><topic>Population studies</topic><topic>Protective equipment</topic><topic>Radiation</topic><topic>Respiration</topic><topic>Respiratory function</topic><topic>Statistical analysis</topic><topic>Statistical tests</topic><topic>Ventilation</topic><topic>washout</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaireit, Till F.</creatorcontrib><creatorcontrib>Gutberlet, Marcel</creatorcontrib><creatorcontrib>Voskrebenzev, Andreas</creatorcontrib><creatorcontrib>Freise, Julia</creatorcontrib><creatorcontrib>Welte, Tobias</creatorcontrib><creatorcontrib>Hohlfeld, Jens M.</creatorcontrib><creatorcontrib>Wacker, Frank</creatorcontrib><creatorcontrib>Vogel‐Claussen, Jens</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaireit, Till F.</au><au>Gutberlet, Marcel</au><au>Voskrebenzev, Andreas</au><au>Freise, Julia</au><au>Welte, Tobias</au><au>Hohlfeld, Jens M.</au><au>Wacker, Frank</au><au>Vogel‐Claussen, Jens</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J Magn Reson Imaging</addtitle><date>2018-06</date><risdate>2018</risdate><volume>47</volume><issue>6</issue><spage>1534</spage><epage>1541</epage><pages>1534-1541</pages><issn>1053-1807</issn><eissn>1522-2586</eissn><abstract>Background
Ventilation‐weighted Fourier decomposition‐MRI (FD‐MRI) has matured as a reliable technique for quantitative measures of regional lung ventilation in recent years, but has yet not been validated in COPD patients.
Purpose/Hypothesis
To compare regional fractional lung ventilation obtained by ventilation‐weighted FD‐MRI with dynamic fluorinated gas washout MRI (19F‐MRI) and lung function test parameters.
Study Type
Prospective study.
Population
Twenty‐seven patients with chronic obstructive pulmonary disease (COPD, median age 61 [54–67] years) were included.
Field Strength/Sequence
For FD‐MRI and for 19F‐MRI a spoiled gradient echo sequence was used at 1.5T.
Assessment
FD‐MRI coronal slices were acquired in free breathing. Dynamic 19F‐MRI was performed after inhalation of 25–30 L of a mixture of 79% fluorinated gas (C3F8) and 21% oxygen via a closed face mask tubing using a dedicated coil tuned to 59.9 MHz. 19F washout times in numbers of breaths (19F‐nbreaths) as well as fractional ventilation maps for both methods (FD‐FV, 19F‐FV) were calculated. Slices were matched using a landmark driven algorithm, and only corresponding slices with an overlap of >90% were coregistered for evaluation.
Statistical Tests
The obtained parameters were correlated with each other using Spearman's correlation coefficient (r).
Results
FD‐FV strongly correlated with 19F‐nbreaths on a global (r = –0.72, P < 0.0001) as well as on a lobar level and with lung function test parameters (FD‐FV vs. FEV1, r = 0.76, P < 0.0001). There was a small systematic overestimation of FD‐FV compared to 19F‐FV (mean difference –0.03 (95% confidence interval [CI]: –0.097; –0.045).
Data Conclusion
Regional ventilation‐weighted Fourier decomposition‐MRI is a promising noninvasive, radiation‐free tool for quantification of regional ventilation in COPD patients.
Level of Evidence: 2
Technical Efficacy: Stage 2
J. Magn. Reson. Imaging 2018;47:1534–1541.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>29160020</pmid><doi>10.1002/jmri.25902</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1053-1807 |
| ispartof | Journal of magnetic resonance imaging, 2018-06, Vol.47 (6), p.1534-1541 |
| issn | 1053-1807 1522-2586 |
| language | eng |
| recordid | cdi_proquest_journals_2047425757 |
| source | Wiley Free Content; Wiley Online Library All Journals |
| subjects | 19F Breathing Chronic obstructive pulmonary disease Confidence intervals COPD Correlation coefficient Correlation coefficients Decomposition Field strength Fluorination Fourier decomposition free breathing Inhalation Lung diseases lung function tests Magnetic resonance imaging Mathematical analysis Obstructive lung disease Parameters Patients Population (statistical) Population studies Protective equipment Radiation Respiration Respiratory function Statistical analysis Statistical tests Ventilation washout |
| title | Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T06%3A58%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20quantitative%20regional%20ventilation%E2%80%90weighted%20fourier%20decomposition%20MRI%20with%20dynamic%20fluorinated%20gas%20washout%20MRI%20and%20lung%20function%20testing%20in%20COPD%20patients&rft.jtitle=Journal%20of%20magnetic%20resonance%20imaging&rft.au=Kaireit,%20Till%20F.&rft.date=2018-06&rft.volume=47&rft.issue=6&rft.spage=1534&rft.epage=1541&rft.pages=1534-1541&rft.issn=1053-1807&rft.eissn=1522-2586&rft_id=info:doi/10.1002/jmri.25902&rft_dat=%3Cproquest_cross%3E2047425757%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2047425757&rft_id=info:pmid/29160020&rfr_iscdi=true |