Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids
A directing group promoting the cyclopropanation of indoles with 2-furylcarbenoids has been developed. These carbenes are derived from enynones and cost-effective ZnI2 is employed as the catalyst for the efficient construction of various polycyclic compounds under mild reaction conditions.
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Veröffentlicht in: | Organic chemistry frontiers an international journal of organic chemistry 2018-06, Vol.5 (11), p.1768-1771 |
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container_issue | 11 |
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container_title | Organic chemistry frontiers an international journal of organic chemistry |
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creator | Chen, Wei Dong-Sheng, Ji Yong-Chun, Luo Zhu-Yin, Wang Peng-Fei, Xu |
description | A directing group promoting the cyclopropanation of indoles with 2-furylcarbenoids has been developed. These carbenes are derived from enynones and cost-effective ZnI2 is employed as the catalyst for the efficient construction of various polycyclic compounds under mild reaction conditions. |
doi_str_mv | 10.1039/c8qo00232k |
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subjects | Carbenes Indoles Organic chemistry Polycyclic compounds |
title | Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids |
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