Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders
Children and adolescents with bipolar disorder (BD) have a high incidence of comorbid attention-deficit/hyperactivity disorder (ADHD). In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in co...
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Veröffentlicht in: | Journal of child and adolescent psychopharmacology 2005-12, Vol.15 (6), p.996-1004 |
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description | Children and adolescents with bipolar disorder (BD) have a high incidence of comorbid attention-deficit/hyperactivity disorder (ADHD). In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in conjunction with mood stabilizers. All patients were outpatients at the Stanford Pediatric Bipolar Disorders Clinic. Information on patients was collected in a retrospective chart review. All but 1 patient demonstrated significant improvement in symptoms of ADHD. No patients had episodes of hypomania or mania during the treatment period. Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD. |
doi_str_mv | 10.1089/cap.2005.15.996 |
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In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in conjunction with mood stabilizers. All patients were outpatients at the Stanford Pediatric Bipolar Disorders Clinic. Information on patients was collected in a retrospective chart review. All but 1 patient demonstrated significant improvement in symptoms of ADHD. No patients had episodes of hypomania or mania during the treatment period. Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. 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In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in conjunction with mood stabilizers. All patients were outpatients at the Stanford Pediatric Bipolar Disorders Clinic. Information on patients was collected in a retrospective chart review. All but 1 patient demonstrated significant improvement in symptoms of ADHD. No patients had episodes of hypomania or mania during the treatment period. Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD.</description><subject>Adolescent</subject><subject>Antimanic Agents - adverse effects</subject><subject>Antimanic Agents - therapeutic use</subject><subject>Atomoxetine Hydrochloride</subject><subject>Attention Deficit Disorder with Hyperactivity - diagnosis</subject><subject>Attention Deficit Disorder with Hyperactivity - drug therapy</subject><subject>Attention deficit hyperactivity disorder</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Bipolar Disorder - drug therapy</subject><subject>Case studies</subject><subject>Children & youth</subject><subject>Comorbidity</subject><subject>Drug Therapy, Combination</subject><subject>Humans</subject><subject>Male</subject><subject>Medical treatment</subject><subject>Prescription drugs</subject><subject>Propylamines - adverse effects</subject><subject>Propylamines - therapeutic use</subject><subject>Retrospective Studies</subject><subject>Teenagers</subject><subject>Treatment Outcome</subject><issn>1044-5463</issn><issn>1557-8992</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpFkE1LAzEQhoMotlbP3iR43zYfm93NsRS_oOBFzyGbzNKUdrMmqVrwx5vSojAwc3ifd-BB6JaSKSWNnBk9TBkhYkrFVMrqDI2pEHXRSMnO803KshBlxUfoKsY1IZRXpLpEI1rxWgpGxuhnnvzWf0NyPeDOB5xWgFMAnbbQJ-w7rFPKl_N9YaFzxqXZaj9A0Ca5T5f22Lrog4WAXY_Nym1sgB7r3mJt_QaiyXDEXy6tcOsGv9Hhj4jX6KLTmwg3pz1B748Pb4vnYvn69LKYLwvDGUtFDY3R2gIXYIFJ3oGgTVeXbUs4bXSp80jgVQ0tbTtJuGCMVdpIybnkGZig-2PvEPzHDmJSa78LfX6pGCkrIijhOTQ7hkzwMQbo1BDcVoe9okQdZKssWx1kKypUlp2Ju1Ptrt2C_c-f7PJf9ml-BA</recordid><startdate>200512</startdate><enddate>200512</enddate><creator>Hah, Mina</creator><creator>Chang, Kiki</creator><general>Mary Ann Liebert, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7RV</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>200512</creationdate><title>Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders</title><author>Hah, Mina ; 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In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in conjunction with mood stabilizers. All patients were outpatients at the Stanford Pediatric Bipolar Disorders Clinic. Information on patients was collected in a retrospective chart review. All but 1 patient demonstrated significant improvement in symptoms of ADHD. No patients had episodes of hypomania or mania during the treatment period. Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc</pub><pmid>16379520</pmid><doi>10.1089/cap.2005.15.996</doi><tpages>9</tpages></addata></record> |
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subjects | Adolescent Antimanic Agents - adverse effects Antimanic Agents - therapeutic use Atomoxetine Hydrochloride Attention Deficit Disorder with Hyperactivity - diagnosis Attention Deficit Disorder with Hyperactivity - drug therapy Attention deficit hyperactivity disorder Bipolar disorder Bipolar Disorder - diagnosis Bipolar Disorder - drug therapy Case studies Children & youth Comorbidity Drug Therapy, Combination Humans Male Medical treatment Prescription drugs Propylamines - adverse effects Propylamines - therapeutic use Retrospective Studies Teenagers Treatment Outcome |
title | Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders |
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