Methodological issues in designing a multisite trial of risperidone in children and adolescents with autism

To describe the methodological challenges and decisions made in developing a multisite, controlled study of risperidone in children and adolescents with autism. Review the design considerations for clinical trials in children with autistic disorder accompanied by severe tantrums, aggressive and/or s...

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Veröffentlicht in:	Journal of child and adolescent psychopharmacology 2001-12, Vol.11 (4), p.377-388
Hauptverfasser:	Scahill, L, McCracken, J, McDougle, C J, Aman, M, Arnold, L E, Tierney, E, Cronin, P, Davies, M, Ghuman, J, Gonzalez, N, Koenig, K, Lindsay, R, Martin, A, McGough, J, Posey, D J, Swiezy, N, Volkmar, F, Ritz, L, Vitiello, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Antipsychotic Agents - adverse effects Antipsychotic Agents - therapeutic use Autism Autistic Disorder - drug therapy Child Child, Preschool Controlled Clinical Trials as Topic Double-Blind Method Female Humans Male Multicenter Studies as Topic Planning Techniques Research Design Risperidone - adverse effects Risperidone - therapeutic use Time Factors
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