IL-21 and TGF-[beta] are required for differentiation of human T^sub H^17 cells

The recent discovery of CD4^sup +^ T cells characterized by secretion of interleukin (IL)-17 (T^sub H^17 cells) and the naturally occurring regulatory FOXP3^sup +^ CD4 T cell (nT^sub reg^) has had a major impact on our understanding of immune processes not readily explained by the T^sub H^1/T^sub H^...

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Veröffentlicht in:	Nature (London) 2008-07, Vol.454 (7202), p.350
Hauptverfasser:	Yang, Li, Anderson, David E, Baecher-Allan, Clare, Hastings, William D, Bettelli, Estelle, Oukka, Mohamed, Kuchroo, Vijay K, Hafler, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune diseases Cells Genotype & phenotype Medical research Monoclonal antibodies Psoriasis Rheumatoid arthritis Skin diseases
Online-Zugang:	Volltext
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