Interleukin-6 Exacerbates Early Atherosclerosis in Mice

Acute-phase proteins, which respond to systemic proinflammatory cytokines such as interleuken-6, are elevated in cardiovascular disease and are predictive markers of future ischemic events, even over decades. This suggests a role for proinflammatory cytokines and/or acute phase proteins in early les...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 1999-10, Vol.19 (10), p.2364-2367
Hauptverfasser:	Huber, S A, Sakkinen, P, Conze, D, Hardin, N, Tracy, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - genetics Arteriosclerosis - chemically induced Arteriosclerosis - immunology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cholesterol - blood Diabetes Mellitus, Type 1 - immunology Interleukin-6 - blood Interleukin-6 - pharmacology Male Medical sciences Mice Mice, Inbred C57BL Mice, Inbred NOD Mice, Knockout Recombinant Proteins - pharmacology Vasculitis - chemically induced Vasculitis - immunology
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