Targeting of carbonic anhydrase IV to plasma membranes is altered in cultured human pancreatic duct cells expressing a mutated ((delta)F508) CFTR
Human pancreatic duct cells secrete HCO3- ions mediated by a Cl-/HCO3- exchanger and a HCO3- channel that may be a carbonic anhydrase IV (CA IV) in a channel-like conformation. This secretion is regulated by CFTR (Cystic Fibrosis Transmembrane conductance Regulator). In CF cells homozygous for the d...
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Veröffentlicht in: | European journal of cell biology 2002-08, Vol.81 (8), p.437 |
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Format: | Artikel |
Sprache: | eng |
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